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Case Studies
Portfolio of non-confidential client projects
Our work often supports ongoing research and long-term partnerships, many of which remain under NDA. The case studies below highlight a few examples we’re able to share publicly. Each project is the result of close collaboration, clear communication, and a deep respect for the science.


Case Studies
Portfolio of non-confidential client projects
Our work often supports ongoing research and long-term partnerships, many of which remain under NDA. The case studies below highlight a few examples we’re able to share publicly—each shaped by close collaboration, clear communication, and a deep respect for the science.


1
Sotagliflozin MOA
Part 4 of a four part series on cellular glucose transporters, SGLT1/SGLT2 inhibition, and cellular energetics related to cardiovascular disease and heart failure. This installment features a newly developed therapeutic option in the treatment of heart disease.
Pharmaceutical

Product MOA

2
Atherosclerosis & Glucose Transporters
Part 3 of a four part series on cellular glucose transporters, SGLT1/SGLT2 inhibition, and cellular energetics related to cardiovascular disease and heart failure. This installment explores the development of cardiovascular disease at the physiological level, and explains the connection between energy homeostasis and the progression of atherosclerosis.
Pharmaceutical

Educational MOD

3
Energy Homeostasis & Heart Failure
Part 2 of a four part series on cellular glucose transporters, SGLT1/SGLT2 inhibition, and cellular energetics related to cardiovascular disease and heart failure. This installment highlights the mechanisms and effects of metabolic energy imbalances on the development of heart failure.
Pharmaceutical

Educational MOD

4
Introduction to Cellular Glucose Transporters
Part 1 of a four part series on cellular glucose transporters, SGLT1/SGLT2 inhibition, and cellular energetics related to cardiovascular disease and heart failure. This installment gives an overview of the two major cell glucose transporter families - GLUTs and SGLTs - and explains their individual locations, functions, and potential as therapeutic targets.
Pharmaceutical

Educational

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1
Sotagliflozin MOA
Part 4 of a four part series on cellular glucose transporters, SGLT1/SGLT2 inhibition, and cellular energetics related to cardiovascular disease and heart failure. This installment features a newly developed therapeutic option in the treatment of heart disease.
December 2023

Product MOA

2
Atherosclerosis & Glucose Transporters
Part 3 of a four part series on cellular glucose transporters, SGLT1/SGLT2 inhibition, and cellular energetics related to cardiovascular disease and heart failure. This installment explores the development of cardiovascular disease at the physiological level, and explains the connection between energy homeostasis and the progression of atherosclerosis.
September 2023

Educational MOD

3
Energy Homeostasis & Heart Failure
Part 2 of a four part series on cellular glucose transporters, SGLT1/SGLT2 inhibition, and cellular energetics related to cardiovascular disease and heart failure. This installment highlights the mechanisms and effects of metabolic energy imbalances on the development of heart failure.
July 2023

Educational MOD

4
Introduction to Cellular Glucose Transporters
Part 1 of a four part series on cellular glucose transporters, SGLT1/SGLT2 inhibition, and cellular energetics related to cardiovascular disease and heart failure. This installment gives an overview of the two major cell glucose transporter families - GLUTs and SGLTs - and explains their individual locations, functions, and potential as therapeutic targets.
January 2023

Educational

- Page 1
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